Multiple Faces Of Deadly Breast Cancer Revealed
An international team of scientists, including four at Simon Fraser University, has made a discovery that will change the way the most deadly form of breast cancer is treated. The journal Nature has just published the team's findings online in the paper The clonal and mutational evolution spectrum of primary triple negative breast cancers. The study is the largest genetic analysis of what were thought to be triple negative breast cancer tumours. The 59 scientists involved in this study expected to see similar gene profiles when they mapped on computer the genomes of 100 tumours.
New Findings For Glioblastoma Presented At AACR
Physician-scientists from University Hospitals (UH) Case Medical Center's Seidman Cancer Center and Case Western Reserve University School of Medicine presented new research findings in 24 presentations at the Annual Meeting of the American Association for Cancer Research (AACR) in Chicago, Illinois. "The breadth and depth of this innovative cancer research presented at AACR is truly outstanding, " says Stan Gerson, MD, Director of the Seidman Cancer Center at UH Case Medical Center and the Case Comprehensive Cancer Center at Case Western Reserve University.
Racial Differences In Breast Cancer Risk Influenced By Vitamin D
American women of African ancestry are more likely than European Americans to have estrogen receptor (ER) negative breast cancer. There continues to be discussion about the role of low levels of vitamin D in the development of breast cancer for these women. New research published in BioMed Central's open access journal Breast Cancer Research has shown that specific genetic variations in the vitamin D receptor (VDR) and in CYP24A1 (responsible for deactivating vitamin D) are associated with an increase in breast cancer risk, particularly for ER negative breast cancer, for African American women.