New Protocols Improve Detection Of MicroRNAs For Diagnosis

MicroRNAs (miRNAs) that regulate processes including fertilization, development, and aging show promise as biomarkers of disease. They can be collected from routinely collected fluids such as blood, saliva, and urine. However, a number of factors can interfere with the accuracy of miRNA tests. In a study published online today in the Journal of Molecular Diagnostics, a group of researchers provide clear procedures for the collection and analysis of miRNA, significantly improving their diagnostic accuracy.

40 Of Cancers Avoidable, UK Research

New research from a leading charity, Cancer Research UK, suggests that around 40% of all cancers are avoidable. More than 100, 000 cases of cancer diagnosed in the UK each year can be directly attributable to cigarettes, diet, alcohol and obesity, and this figure raises to 134, 000 when taking into account over a dozen lifestyle and environmental risk factors, according to a review published as a series of research papers in a supplementary 6 December issue of the British Journal of Cancer.

Combination Of Everolimus And Exemestane Improves Progression-Free Survival For Women With Metastatic Breast Cancer

In an international Phase III randomized study, everolimus, when combined with the hormonal therapy exemestane, has been shown to dramatically improve progression-free survival, according to research from The University of Texas MD Anderson Cancer Center. The study, known as Breast Cancer Trials of Oral Everolimus (BOLERO-2), was presented at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium by Gabriel Hortobagyi, M.D., professor and chair of MD Anderson's Department of Breast Medical Oncology.