Breast Cancer Cells Transformed Into Cancer Stem Cells By Radiation Treatment
Breast cancer stem cells are thought to be the sole source of tumor recurrence and are known to be resistant to radiation therapy and don't respond well to chemotherapy. Now, researchers with the UCLA Department of Radiation Oncology at UCLA's Jonsson Comprehensive Cancer Center report for the first time that radiation treatment - despite killing half of all tumor cells during every treatment - transforms other cancer cells into treatment-resistant breast cancer stem cells. The generation of these breast cancer stem cells counteracts the otherwise highly efficient radiation treatment.
Survival In Medulloblastoma Model Extended By Oncolytic Virus
A strain of measles virus engineered to kill cancer cells prolongs survival in a model of medulloblastoma that is disseminated in the fluid around the brain, according to a new study by researchers at Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute and the Mayo Clinic. Treatment with the oncolytic virus called MV-GFP extended survival of animals with disseminated human medulloblastoma up to 122 percent, with treated animals surviving 82 days on average versus 37 days for controls.
Study Finds Female Cancer Survivors Have Worse Health Behaviors Than Women With No Cancer History
A recent study conducted by researchers at Moffitt Cancer Center in Tampa, Fla., and the Mayo Clinic in Rochester, Minn., has found that female cancer survivors receiving screening mammography have "worse health behaviors" than women receiving mammography screening and who had never had cancer. The study was published in a recent issue of the American Journal of Clinical Oncology. Researchers surveyed 19, 948 women age 35 and older presenting for screening mammography with no prior breast cancer and compared their responses of 2, 713 cancer survivors, also receiving screening mammography.