Biomarkers May Predict Chemo-Resistant Breast Cancers
Researchers at the University of Hull in the UK have identified a family of proteins that could potentially be used as biomarkers to predict resistance to chemotherapy in estrogen receptor-positive (ER-positive) breast cancer patients. In an "in press" issue of their study published online in the Journal of Proteomics on 3 April, lead researcher Dr Lynn Cawkwell and colleagues explain how they discovered a number of potential biomarkers for resistance to epirubicin, docetaxel and other chemo drugs.
60 Bowel Cancer Death-Rate Drop By 2025 Possible, Says Bowel Cancer UK
According to a new report, the '2025 Challenge: Saving and Improving Lives' from Bowel Cancer UK, the Government could reduce bowel cancer deaths by 60% by 2025, if it follows the recommendations of its new report. In the UK, bowel cancer is the second largest cancer killer, with an overall five-year survival rate of just over 50% of those who are diagnosed. Bowel Cancer UK also aims that an additional 2, 500 people with bowel cancer, per year, live for at least five years after diagnosis by 2025.
Altering Tumor Microenvironment Shown To Boost Response To Cancer Drugs During Live Imaging
It should be possible to significantly improve the response of common cancers to existing "classical" chemotherapy drugs, say scientists at Cold Spring Harbor Laboratory (CSHL), by introducing agents that alter the interaction of cancer cells with their immediate surroundings, called the tumor microenvironment. In research published online in the journal Cancer Cell, CSHL Assistant Professor Mikala Egeblad and her team report using "live" microscopy to observe how cancer cells in mouse tumors react to the widely used chemotherapeutic agent doxorubicin.