Link Between Childhood Obesity And Increased Risk Of Hepatocellular Carcinoma In Adulthood
Childhood obesity is a widespread global epidemic (1) and in parallel with non-alcoholic fatty liver disease (NAFLD)(2) is now the leading cause of liver disease among children. New data presented at the International Liver Congress™ 2012 furthers this concern by showing that childhood obesity is positively linked with developing hepatocellular carcinoma (HCC) - the most common form of liver cancer(3) - in adulthood.(4) The Danish study monitored birth weight and BMI at school age of 165, 540 men and 160, 883 women born between1930 and 1989.
News From The Annals Of Internal Medicine: May 1, 2012
1. For Younger Women at Increased Risk for Breast Cancer, Benefits of Mammography Screening Outweigh Harms According to two new studies being published in Annals of Internal Medicine, younger women at increased risk for breast cancer may benefit from biennial mammography screening beginning at age 40. Currently, major organizations with mammography screening guidelines do not have a consensus on whether to routinely screen all women in their 40s. These data have implications for risk-based screening programs.
Protein Vital For Cell Survival And Immune Balance Has Another Form With A Different Function, Could Yield Additional Cancer Treatment Strategy
Research led by St. Jude Children's Research Hospital investigators suggests that safeguarding cell survival and maintaining a balanced immune system is just the start of the myeloid cell leukemia sequence 1 (MCL1) protein's work. Nearly 20 years after MCL1 was discovered, scientists have identified a second form of the protein that works in a different location in cells and performs a different function. This newly identified version is shorter and toils inside rather than outside mitochondria where it assists in production of chemical energy that powers cells.