A Breakthrough In Understanding The Biology And Treatment Of Ovarian Cancer
Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that the presence and integrity of the opioid growth factor receptor (OGFr), which mediates the inhibitory action of opioid growth factor (OGF) on cell proliferation, is a key to understanding the progression and treatment of human ovarian cancer. Transplantation of human ovarian cancer cells that were molecularly engineered to have a reduced expression of OGFr, into immunocompromised mice resulted in ovarian tumors that grew rapidly.
Brain Cancer Blood Vessels Not Substantially Tumor-Derived
Johns Hopkins scientists have published laboratory data refuting studies that suggest blood vessels that form within brain cancers are largely made up of cancer cells. The theory of cancer-based blood vessels calls into question the use and value of anticancer drugs that target these blood vessels, including bevacizumab ( Avastin ). "We don't question whether brain cancer cells have the potential to express blood vessel markers and may occasionally find their way into blood vessels, but we do question the extent to which this happens, " says Charles Eberhart, M.
Discussions Of Infertility Risks Between Radiation Oncologists And Young Cancer Patients
Quality-of-life issues gaining prominence as long-term cancer survival rates increase More than 80 percent of radiation oncologists discuss the impact of cancer treatments on fertility with their patients of childbearing age, which can lead to improved quality of life for young cancer patients who are living much longer after their original diagnosis thanks to modern treatment options, according to a study in Practical Radiation Oncology (PRO), the official clinical practice journal of the American Society for Radiation Oncology (ASTRO).