Findings In Songbirds May Have Important Implications For Brain Degeneration In Humans
Colin Saldanha, a biology professor at American University in Washington, D.C., has always been intrigued by the hormone estrogen. Specifically, how the hormone that does so much (for example, it promotes sexual behavior in women but can also increase susceptibility to seizures) does not cause major cross circuit meltdowns. "In the extreme case, once every 28 days, women should be having seizures - and when they do, it's a condition called Catamenial Epilepsy - but that's obviously not the norm and there's the mystery, " Saldanha said.
Novartis Announces Termination Of ALTITUDE Study With Rasilez reg; Tekturna reg; In High-Risk Patients With Diabetes And Renal Impairment
Novartis announced that following the seventh interim review of data from the ALTITUDE study with Rasilez® /Tekturna® (aliskiren), a decision to terminate the trial has been taken on the recommendation of the independent Data Monitoring Committee (DMC) overseeing the trial. The DMC concluded that patients were unlikely to benefit from treatment added on top of standard anti-hypertensives, and identified higher adverse events in patients receiving Rasilez/Tekturna in addition to standard of care in the trial.
Researchers Discover Protein That May Represent New Target For Treating Type 1 Diabetes
Researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine and colleagues have discovered a new protein that may play a critical role in how the human body regulates blood sugar levels. Reporting in the current issue of Pancreas, the research team says the protein may represent a new target for treating type 1 diabetes. "This data may change the current thinking about what causes type 1 diabetes, " said Bryon E. Petersen, Ph.D., professor of regenerative medicine and senior author.