New Candidate Vaccine Neutralizes All Tested Strains Of Malaria Parasite
A new candidate malaria vaccine with the potential to neutralise all strains of the most deadly species of malaria parasite has been developed by a team led by scientists at the University of Oxford. The results of this new vaccine independently confirm the utility of a key discovery reported last month from scientists at the Wellcome Trust Sanger Institute who had identified this target within the parasite as a potential 'Achilles' heel' that could hold significant promise for vaccine development.
Study Details How Dengue Infection Hits Harder The Second Time Around
One of the most vexing challenges in the battle against dengue virus, a mosquito-borne virus responsible for 50-100 million infections every year, is that getting infected once can put people at greater risk for a more severe infection down the road. Now, for the first time, an international team of researchers that includes experts from the University of California, Berkeley, has pulled apart the mechanism behind changing dengue virus genetics and dynamics of host immunity, and they are reporting their findings in the Dec.
Broader Vaccines - Targeting Cell Membrane Proteins
A study published online in Immunity reveals that by stimulating specialized immune cells to identify foreign cell membrane proteins that are shared across bacterial species, scientists may be able to develop vaccines with a broader reach. The researchers of the study from the Children's Hospital of Pittsburgh of UPMS and the University of Pittsburgh School of Medicine say that this strategy could prove especially beneficial in preventing infections caused by multi-drug resistant organisms. Senior author Jay K.