Same Mechanism As For DNA Employed As Protein Networks Stabilize Muscle Fibers
The same mechanism that stabilises the DNA in the cell nucleus is also important for the structure and function of vertebrate muscle cells. This has been established by RUB-researchers led by Prof. Dr. Wolfgang Linke (Institute of Physiology) in cooperation with American and German colleagues. An enzyme attaches a methyl group to the protein Hsp90, which then forms a complex with the muscle protein titin. When the researchers disrupted this protein network through genetic manipulation in zebrafish the muscle structure partly disintegrated.
Bone Mineral Density Screening For Older Women With Normal T-Scores May Not Needed For 15 Years
The U.S. Preventive Services Task Force and other organizations have recommended that women ages 65 and older be routinely screened for osteoporosis using bone mineral density (BMD) screening. However, how often women should be screened is a topic that remains controversial and undecided, with no definitive scientific evidence to provide guidance. Now a new study led by Margaret L. Gourlay, MD, MPH of the University of North Carolina at Chapel Hill School of Medicine finds that women aged 67 years and older with normal bone mineral density scores may not need screening again for 15 years.
Blood Clots After Hip Or Knee Replacement - Study Looks At Prevalence
According to a study in the January 18 issue of JAMA, approximately 1 in every 100 patients undergoing knee replacement surgery, and 1 in every 200 patients undergoing hip replacement surgery who use current preventive medications for venous thromboembolism (VTE; a blood clot that develops within a vein that might become serious), will develop VTE before being discharged from hospital. In acute care hospitals, a crucial safety issue is postoperative VTE, which includes pulmonary embolism and deep vein thrombosis (DVT).