Kids' Bone Disorder, Hypophosphatasia, Treatment Shows Promise
According to a study published in the March 8 issue of the New England Journal of Medicine, a promising new treatment for hypophosphatasia (HHP) - a rare and occasionally fatal bone disorder that can affect infants and young children - has been identified by a team of doctors at Washington University School of Medicine in St. Louis, in collaboration with Shriners Hospital for Children and other institutions. The condition is a rare, inherited disease that affects bones and teeth. It upsets bone metabolism by preventing vital minerals, such as calcium, from depositing in the skeleton.
First Classification Criteria For Polymyalagia Rheumatica Released By American College Of Rheumatology
The American College of Rheumatology has released the first classification criteria for polymyalgia rheumatica - aimed at helping physicians identify patients with this condition, which occurs in persons aged 50 years or older who have recent onset of pain in the shoulders, neck and hips along with other inflammatory symptoms not explained by an alternate diagnosis. Polymyalgia rheumatica is a relatively common cause of widespread aching and stiffness in older adults. It can be difficult to diagnose because it rarely causes swollen joints or other abnormalities on physical exam.
Catch-Up Growth By Various Diets And Resveratrol Intervention And The Effect On Bone Status
Although many current studies focused on catch up growth (CUG) have described its high susceptibility to insulin resistance-related diseases very few have focused on the effect of CUG on bone metabolism, especially in adulthood. As diet is a controllable factor, the influence of re-feeding with different dietary patterns on bone parameters is important to study. Resveratrol has been attributed a number of beneficial effects in mammals including osteotrophic properties. In the March 2012 issue of Experimental Biology and Medicine Wang and colleagues describe the first study to describe the effects of CUG, with different diets, on bone status and the role of resveratrol in CUG models.